In vivo solid phase microextraction for therapeutic monitoring and pharmacometabolomic fingerprinting of lung during in vivo lung perfusion of FOLFOX

• Main Authors: Nikita Looby (Author), Anna Roszkowska (Author), Miao Yu (Author), German Rios-Gomez (Author), Mauricio Pipkin (Author), Barbara Bojko (Author), Marcelo Cypel (Author), Janusz Pawliszyn (Author)
• Format: Book
• Published: Elsevier, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In vivo lung perfusion (IVLP) is a novel isolated lung technique developed to enable the local, in situ administration of high-dose chemotherapy to treat metastatic lung cancer. Combination therapy using folinic acid (FOL), 5-fluorouracil (F), and oxaliplatin (OX) (FOLFOX) is routinely employed to t...