Endotoxin Tolerance in Abdominal Aortic Aneurysm Macrophages, In Vitro: A Case-Control Study

• Main Authors: Lara T. Meital (Author), Mark T. Windsor (Author), Alesiya E. Maynard (Author), Karl Schulze (Author), Rebecca Magee (Author), Jill O'Donnell (Author), Pankaj Jha (Author), Chaim Y. Meital (Author), Maria Perissiou (Author), Steven Coverdale (Author), Jonathan Golledge (Author), Anna V. Kuballa (Author), Tom G. Bailey (Author), Christopher D. Askew (Author), Fraser D. Russell (Author)
• Format: Book
• Published: MDPI AG, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macrophages are implicated in the pathogenesis of abdominal aortic aneurysm (AAA). This study examined the environmentally conditioned responses of AAA macrophages to inflammatory stimuli. Plasma- and blood-derived monocytes were separated from the whole blood of patients with AAA (30-45 mm diameter...