Development and Validation of a Novel UHPLC-MS/MS Method for the Quantification of Plinabulin in Plasma and Its Application in a Pharmacokinetic Study with Leukopenic Rats

Plinabulin, a new antitumor drug developed from marine natural products that targets microtubules in cancer cells, is currently being tested in a phase III clinical study. Plinabulin has been clinically proven to be effective on leukopenia. However, to our knowledge, there are no reports investigati...

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Main Authors: Xiaochen Niu (Author), Dan Chen (Author), Wei He (Author), Yu Tang (Author), Jianchun Zhao (Author)
Format: Book
Published: MDPI AG, 2023-08-01T00:00:00Z.
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3rd Floor Main Library

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