RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection.

• Main Authors: A M A Nasirudeen (Author), Hui Hui Wong (Author), Peiling Thien (Author), Shengli Xu (Author), Kong-Peng Lam (Author), Ding Xiang Liu (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue virus (DV) infection is one of the most common mosquito-borne viral diseases in the world. The innate immune system is important for the early detection of virus and for mounting a cascade of defense measures which include the production of type 1 interferon (IFN). Hence, a thorough understan...