BCL7A is silenced by hypermethylation to promote acute myeloid leukemia

• Main Authors: Juan Rodrigo Patiño-Mercau (Author), Carlos Baliñas-Gavira (Author), Alvaro Andrades (Author), Maria S. Benitez-Cantos (Author), Ana Ercegovič Rot (Author), Maria Isabel Rodriguez (Author), Juan Carlos Álvarez-Pérez (Author), Marta Cuadros (Author), Pedro P. Medina (Author)
• Formato: Livro
• Publicado em: BMC, 2023-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Recent massive sequencing studies have revealed that SWI/SNF complexes are among the most frequently altered functional entities in solid tumors. However, the role of SWI/SNF in acute myeloid leukemia is poorly understood. To date, SWI/SNF complexes are thought to be oncogenic in...