Power to identify exposure‐response relationships in phase IIa pulmonary tuberculosis trials with multi‐dimensional bacterial load modeling

Abstract Adequate power to identify an exposure‐response relationship in a phase IIa clinical trial for pulmonary tuberculosis (TB) is important for dose selection and design of follow‐up studies. Currently, it is not known what response marker provides the pharmacokinetic‐pharmacodynamic (PK‐PD) mo...

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Bibliographic Details
Main Authors: Simon E. Koele (Author), Thomas P. C. Dorlo (Author), Caryn M. Upton (Author), Rob E. Aarnoutse (Author), Elin M. Svensson (Author)
Format: Book
Published: Wiley, 2024-03-01T00:00:00Z.
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3rd Floor Main Library

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