In situ injectable hydrogel encapsulating Mn/NO-based immune nano-activator for prevention of postoperative tumor recurrence

• Main Authors: Shengnan Huang (Author), Chenyang Zhou (Author), Chengzhi Song (Author), Xiali Zhu (Author), Mingsan Miao (Author), Chunming Li (Author), Shaofeng Duan (Author), Yurong Hu (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Postoperative tumor recurrence remains a predominant cause of treatment failure. In this study, we developed an in situ injectable hydrogel, termed MPB-NO@DOX + ATRA gel, which was locally formed within the tumor resection cavity. The MPB-NO@DOX + ATRA gel was fabricated by mixing a thrombin solutio...