Unequivocal identification of subpopulations in putative multiclonal Trypanosoma cruzi strains by FACs single cell sorting and genotyping.

• Main Authors: Helder Magno Silva Valadares (Author), Juliana Ramos Pimenta (Author), Marcela Segatto (Author), Vanja Maria Veloso (Author), Mônica Lúcia Gomes (Author), Egler Chiari (Author), Kenneth John Gollob (Author), Maria Terezinha Bahia (Author), Marta de Lana (Author), Glória Regina Franco (Author), Carlos Renato Machado (Author), Sérgio Danilo Junho Pena (Author), Andréa Mara Macedo (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trypanosoma cruzi, the etiological agent of Chagas disease, is a polymorphic species. Evidence suggests that the majority of the T. cruzi populations isolated from afflicted humans, reservoir animals, or vectors are multiclonal. However, the extent and the complexity of multiclonality remain to be e...