Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications

• Main Authors: Stefan Wolking (Author), Ciarán Campbell (Author), Caragh Stapleton (Author), Mark McCormack (Author), Norman Delanty (Author), Chantal Depondt (Author), Michael R. Johnson (Author), Bobby P. C. Koeleman (Author), Roland Krause (Author), Wolfram S. Kunz (Author), Anthony G. Marson (Author), Josemir W. Sander (Author), Graeme J. Sills (Author), Pasquale Striano (Author), Federico Zara (Author), Sanjay M. Sisodiya (Author), Gianpiero L. Cavalleri (Author), Holger Lerche (Author), EpiPGX Consortium (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Resistance to anti-seizure medications (ASMs) presents a significant hurdle in the treatment of people with epilepsy. Genetic markers for resistance to individual ASMs could support clinicians to make better-informed choices for their patients. In this study, we aimed to elucidate whether...