Characterising Cytokine Gene Expression Signatures in Patients with Severe Sepsis

• Main Authors: Robert Grealy (Author), Mary White (Author), Patrick Stordeur (Author), Dermot Kelleher (Author), Derek G. Doherty (Author), Ross McManus (Author), Thomas Ryan (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction. Severe sepsis in humans may be related to an underlying profound immune suppressive state. We investigated the link between gene expression of immune regulatory cytokines and the range of illness severity in patients with infection and severe sepsis. Methods. A prospective observationa...