Quartz Dust Exposure Affects NLRP3 Inflammasome Activation and Plasma Levels of IL-18 and IL-1Ra in Iron Foundry Workers

• Main Authors: Alexander Hedbrant (Author), Lena Andersson (Author), Ing-Liss Bryngelsson (Author), Daniel Eklund (Author), Håkan Westberg (Author), Eva Särndahl (Author), Alexander Persson (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose. To study the association between inhalation of particulate matter or quartz in Swedish iron foundries and the effects on NLRP3 inflammasome activation. Methods. Particle exposure measurements were performed during an eight-hour work day for 85 foundry workers at three Swedish iron foundries...