Asymmetric expression of H19 and ADIPOQ in concave/convex paravertebral muscles is associated with severe adolescent idiopathic scoliosis

• Main Authors: Heng Jiang (Author), Fu Yang (Author), Tao Lin (Author), Wei Shao (Author), Yichen Meng (Author), Jun Ma (Author), Ce Wang (Author), Rui Gao (Author), Xuhui Zhou (Author)
• Format: Book
• Published: BMC, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Adolescent idiopathic scoliosis (AIS) is the most common paediatric spinal deformity. The etiology and pathology of AIS remain unexplained, and have been reported to involve a combination of genetic and epigenetic factors. Since paravertebral muscle imbalance plays an important r...