Model‐based meta‐analysis to quantify the effects of short interfering RNA therapeutics on hepatitis B surface antigen turnover in hepatitis B‐infected mice

• Main Authors: Louis Sandra (Author), Huybrecht T'jollyn (Author), An Vermeulen (Author), Oliver Ackaert (Author), Juan‐Jose Perez‐Ruixo (Author)
• Format: Book
• Published: Wiley, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The objective of this study was to compare the efficacy of short interfering RNA therapeutics (siRNAs) in reducing hepatitis B surface antigen (HBsAg) levels in hepatitis B‐infected (HBV) mice across multiple siRNA therapeutic classes using model‐based meta‐analysis (MBMA) techniques. Liter...