Triplex-forming oligonucleotides as an anti-gene technique for cancer therapy
Triplex-forming oligonucleotides (TFOs) can bind to the major groove of double-stranded DNA with high specificity and affinity and inhibit gene expression. Triplex-forming oligonucleotides have gained prominence because of their potential applications in antigene therapy. In particular, the target s...
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Frontiers Media S.A.,
2022-12-01T00:00:00Z.
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