Targeting aberrant glycosylation to modulate microglial response and improve cognition in models of Alzheimer's disease

• Main Authors: Yue Wang (Author), Yixuan Du (Author), Hongfei Huang (Author), Yiming Cao (Author), Kemeng Pan (Author), Yueqian Zhou (Author), Jiawei He (Author), Wenbing Yao (Author), Song Chen (Author), Xiangdong Gao (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Altered glycosylation profiles have been correlated with potential drug targets in various diseases, including Alzheimer's disease (AD). In this area, the linkage between bisecting N-acetylglucosamine (GlcNAc), a product of N-acetylglucosaminyltransferase III (GnT-III), and AD has been recogniz...