Construction and stable gene expression of AGR2xPD1 bi-specific antibody that enhances attachment between T-Cells and lung tumor cells, suppress tumor cell migration and promoting CD8 expression in cytotoxic T-cells

• Main Authors: Debmalya Roy (Author), Guo-Song Liu (Author), Aru Zeling Wang (Author), Bingjie Zhou (Author), Fakhar- (Author), Ghulam Raza (Author), Siva Bharath Merugu (Author), Dhahiri Saidi Mashausi (Author), Dawei Li (Author), Bo Zhao (Author)
• Format: Book
• Published: Elsevier, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There has been a substantial and consistent rise in the number of clinical trials to develop advanced and potent bispecific antibodies (BsAb) over the past two decades with multiple targets to improve the efficacy or tissue specificity of monoclonal antibodies (mAb) treatment for diseases with multi...