Pdgfrα functions in endothelial-derived cells to regulate neural crest cells and the development of the great arteries

• मुख्य लेखकों: Haig Aghajanian (लेखक), Young Kuk Cho (लेखक), Nicholas W. Rizer (लेखक), Qiaohong Wang (लेखक), Li Li (लेखक), Karl Degenhardt (लेखक), Rajan Jain (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2017-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Originating as a single vessel emerging from the embryonic heart, the truncus arteriosus must septate and remodel into the aorta and pulmonary artery to support postnatal life. Defective remodeling or septation leads to abnormalities collectively known as conotruncal defects, which are associated wi...