Hypertrophic cardiomyopathy is characterized by alterations of the mitochondrial calcium uniporter complex proteins: insights from patients with aortic valve stenosis versus hypertrophic obstructive cardiomyopathy

• Main Authors: Vera Paar (Author), Michael Haslinger (Author), Philipp Krombholz-Reindl (Author), Stefan Pittner (Author), Matthias Neuner (Author), Peter Jirak (Author), Tobias Kolbitsch (Author), Bernd Minnich (Author), Falk Schrödl (Author), Alexandra Kaser-Eichberger (Author), Kristen Kopp (Author), Andreas Koller (Author), Clemens Steinwender (Author), Michael Lichtenauer (Author), Fabio C. Monticelli (Author), Rainald Seitelberger (Author), Uta C. Hoppe (Author), Christian Dinges (Author), Lukas J. Motloch (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Hypertrophies of the cardiac septum are caused either by aortic valve stenosis (AVS) or by congenital hypertrophic obstructive cardiomyopathy (HOCM). As they induce cardiac remodeling, these cardiac pathologies may promote an arrhythmogenic substrate with associated malignant ventricul...