Characterization of glioblastoma spheroid models for drug screening and phototherapy assays

• 主要な著者: Samara Rodrigues Alves (著者), Italo Rodrigo Calori (著者), Hong Bi (著者), Antonio Claudio Tedesco (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2023-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Glioblastoma (GBM) spheroids present as a promising alternative testing platform for in vivo models of brain cancer, aiming at the 3Rs principle of animal use in pre-clinical trials. However, the poor characterization and irreproducibility of various GBM-based spheroids have hampered the achievement...