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Phosphodiesterase 10A Is a Mediator of Osteogenic Differentiation and Mechanotransduction in Bone Marrow-Derived Mesenchymal Stromal Cells

Bone marrow-derived mesenchymal stromal cells (hMSCs) are capable of differentiating into the osteogenic lineage, and for osteogenic differentiation, mechanical loading is a relevant stimulus. Mechanotransduction leads to the formation of second messengers such as cAMP, cGMP, or Ca2+ influx resultin...

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Main Authors: Sigrid Müller-Deubert (Author), Carolin Ege (Author), Melanie Krug (Author), Jutta Meißner-Weigl (Author), Maximilian Rudert (Author), Oliver Bischof (Author), Franz Jakob (Author), Regina Ebert (Author)
Format: Book
Published: Hindawi Limited, 2020-01-01T00:00:00Z.
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