Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension

• Main Authors: Krusius Tom (Author), Virtamo Jarmo (Author), Miettinen Helena E (Author), Piippo Kirsi (Author), Fodstad Heidi (Author), Helin Karri (Author), Fyhrquist Frej (Author), Tikkanen Tuula (Author), Tikkanen Ilkka (Author), Kontula Kimmo (Author), Hannila-Handelberg Tuula (Author), Sarna Seppo (Author), Gautschi Ivan (Author), Schild Laurent (Author), Hiltunen Timo P (Author)
• Format: Book
• Published: BMC, 2005-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Rare mutations of the epithelial sodium channel (ENaC) result in the monogenic hypertension form of Liddle's syndrome. We decided to screen for common variants in the ENaC βand γ subunits in patients with essential hypertension...