Peripheral non-viral MIDGE vector-driven delivery of β-endorphin in inflammatory pain

• Main Authors: Busch Melanie (Author), Labuz Dominika (Author), Brack Alexander (Author), Rittner Heike L (Author), Mousa Shaaban A (Author), Sitte Nicolle (Author), Binder Waltraud (Author), Schroff Matthias (Author), Oswald Detlef (Author), Machelska Halina (Author), Wittig Burghardt (Author), Schäfer Michael (Author), Stein Christoph (Author)
• Format: Book
• Published: SAGE Publishing, 2009-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Leukocytes infiltrating inflamed tissue produce and release opioid peptides such as β-endorphin, which activate opioid receptors on peripheral terminals of sensory nerves resulting in analgesia. Gene therapy is an attractive strategy...