<i>Nox</i>2 Deficiency Reduces Cartilage Damage and Ectopic Bone Formation in an Experimental Model for Osteoarthritis

• Main Authors: Nik N. L. Kruisbergen (Author), Irene Di Ceglie (Author), Yvonne van Gemert (Author), Birgitte Walgreen (Author), Monique M. A. Helsen (Author), Annet W. Slöetjes (Author), Marije I. Koenders (Author), Fons A. J. van de Loo (Author), Johannes Roth (Author), Thomas Vogl (Author), Peter M. van der Kraan (Author), Arjen B. Blom (Author), Peter L. E. M. van Lent (Author), Martijn H. J. van den Bosch (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoarthritis (OA) is a destructive disease of the joint with age and obesity being its most important risk factors. Around 50% of OA patients suffer from inflammation of the synovial joint capsule, which is characterized by increased abundance and activation of synovial macrophages that produce re...