The improved antitumor efficacy of continuous intratumoral chemotherapy with cisplatin-loaded implants for the treatment of sarcoma 180 tumor-bearing mice

• Main Authors: Li Gao (Author), Shang Cai (Author), Awei Cai (Author), Yang Zhao (Author), Tangbing Xu (Author), Yan Ma (Author), Yan Xu (Author), Yuan Wang (Author), Hao Wang (Author), Yong Hu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cisplatin is the most commonly used antitumor drug in the chemotherapy of a variety of malignancies. However, the severe side effects and drug resistance limit its clinical application. The aim of this study was to develop PLGA-based cisplatin-loaded implants and evaluate the antitumor efficacy of c...