Exosomal miR-590-3p derived from cancer-associated fibroblasts confers radioresistance in colorectal cancer

• Main Authors: Xijuan Chen (Author), Yingqiang Liu (Author), Qinglan Zhang (Author), Baoxing Liu (Author), Yan Cheng (Author), Yonglei Zhang (Author), Yanan Sun (Author), Junqi Liu (Author)
• Format: Book
• Published: Elsevier, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Radiotherapeutic resistance is a major obstacle for the effective treatment of colorectal cancer (CRC). MicroRNAs (miRNAs) play a critical role in chemoresistance and radioresistance. Here, we aimed to investigate whether miR-590-3p participates in the radioresistance of CRC. High expression of miR-...