Peripheral Protein Quality Control as a Novel Drug Target for CFTR Stabilizer

Conformationally defective cystic fibrosis transmembrane conductance regulator (CFTR) including rescued ΔF508-CFTR is rapidly eliminated from the plasma membrane (PM) even in the presence of a CFTR corrector and potentiator, limiting the therapeutic effort of the combination therapy. CFTR eliminatio...

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Bibliographic Details
Main Authors: Ryosuke Fukuda (Author), Tsukasa Okiyoneda (Author)
Format: Book
Published: Frontiers Media S.A., 2018-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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