Peripheral Protein Quality Control as a Novel Drug Target for CFTR Stabilizer
Conformationally defective cystic fibrosis transmembrane conductance regulator (CFTR) including rescued ΔF508-CFTR is rapidly eliminated from the plasma membrane (PM) even in the presence of a CFTR corrector and potentiator, limiting the therapeutic effort of the combination therapy. CFTR eliminatio...
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| Main Authors: | , |
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| Format: | Book |
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Frontiers Media S.A.,
2018-09-01T00:00:00Z.
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