Posttranslational modification and beyond: interplay between histone deacetylase 6 and heat-shock protein 90

• Main Authors: Ping Liu (Author), Ji Xiao (Author), Yiliang Wang (Author), Xiaowei Song (Author), Lianzhou Huang (Author), Zhe Ren (Author), Kaio Kitazato (Author), Yifei Wang (Author)
• Formato: Livro
• Publicado em: BMC, 2021-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Posttranslational modification (PTM) and regulation of protein stability are crucial to various biological processes. Histone deacetylase 6 (HDAC6), a unique histone deacetylase with two functional catalytic domains (DD1 and DD2) and a ZnF-UBP domain (ubiquitin binding domain, BUZ), regulat...