Breakpoint Associated with a novel 2.3 Mb deletion in the VCFS region of 22q11 and the role of <it>Alu </it>(SINE) in recurring microdeletions

• Main Authors: O'Reilly Richard L (Author), Fan Yao-Shan (Author), Siu Victoria (Author), Zhang Yang (Author), Uddin Raihan K (Author), Rao Jay (Author), Singh Shiva M (Author)
• Format: Book
• Published: BMC, 2006-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Chromosome 22q11.2 region is highly susceptible to rearrangement, specifically deletions that give rise to a variety of genomic disorders including velocardiofacial or DiGeorge syndrome. Individuals with this 22q11 microdeletion synd...