Testing the Stability of Drug Resistance on Cryopreserved, Gene-Engineered Human Induced Pluripotent Stem Cells

• Main Authors: Dilaware Khan (Author), Ann-Christin Nickel (Author), Sebastian Jeising (Author), Constanze Uhlmann (Author), Sajjad Muhammad (Author), Daniel Hänggi (Author), Igor Fischer (Author), Ulf Dietrich Kahlert (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human induced pluripotent stem cells (hiPSCs) have emerged as a powerful tool for in vitro modelling of diseases with broad application in drug development or toxicology testing. These assays usually require large quantities of hiPSC, which can entail long-term storage via cryopreservation of the sa...