Genomes of Leishmania parasites directly sequenced from patients with visceral leishmaniasis in the Indian subcontinent.

• Main Authors: Malgorzata A Domagalska (Author), Hideo Imamura (Author), Mandy Sanders (Author), Frederik Van den Broeck (Author), Narayan Raj Bhattarai (Author), Manu Vanaerschot (Author), Ilse Maes (Author), Erika D'Haenens (Author), Keshav Rai (Author), Suman Rijal (Author), Matthew Berriman (Author), James A Cotton (Author), Jean-Claude Dujardin (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Whole genome sequencing (WGS) is increasingly used for molecular diagnosis and epidemiology of infectious diseases. Current Leishmania genomic studies rely on DNA extracted from cultured parasites, which might introduce sampling and biological biases into the subsequent analyses. Up to now, direct a...