Learn from failures and stay hopeful to GPR40, a GPCR target with robust efficacy, for therapy of metabolic disorders
GPR40 is a class A G-protein coupled receptor (GPCR) mainly expressed in pancreas, intestine, and brain. Its endogenous ligand is long-chain fatty acids, which activate GPR40 after meal ingestion to induce secretion of incretins in the gut, including GLP-1, GIP, and PYY, the latter control appetite...
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| Main Authors: | , |
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| Format: | Book |
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Frontiers Media S.A.,
2022-10-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |