Heme Oxygenase-1 Overexpression Promotes Uveal Melanoma Progression and Is Associated with Poor Clinical Outcomes

• Main Authors: Lucia Longhitano (Author), Giuseppe Broggi (Author), Sebastiano Giallongo (Author), Maria Failla (Author), Lidia Puzzo (Author), Teresio Avitabile (Author), Daniele Tibullo (Author), Alfio Distefano (Author), Valeria Pittalà (Author), Michele Reibaldi (Author), Guido Nicola Zanghì (Author), Antonio Longo (Author), Andrea Russo (Author), Rosario Caltabiano (Author), Giovanni Li Volti (Author), Nicolò Musso (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Uveal melanoma (UM) is the most common primary intraocular tumor in adults. To date, the main strategies to counteract its progression consist of focal radiation on the tumor site and ocular enucleation. Furthermore, many UM patients develop liver metastasis within 10 years following diagnosis, even...