Design, Synthesis, In Silico Testing, and In Vitro Evaluation of Thiazolidinone-Based Benzothiazole Derivatives as Inhibitors of α-Amylase and α-Glucosidase

• Egile Nagusiak: Shoaib Khan (Egilea), Shahid Iqbal (Egilea), Marwa Khan (Egilea), Wajid Rehman (Egilea), Mazloom Shah (Egilea), Rafaqat Hussain (Egilea), Liaqat Rasheed (Egilea), Yousaf Khan (Egilea), Ayed A. Dera (Egilea), Rami Adel Pashameah (Egilea), Eman Alzahrani (Egilea), Abd-ElAziem Farouk (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

In this study, a stepwise reaction afforded thiazolidinone-based benzothiazole derivatives <b>1</b>-<b>15</b>, and the synthesized derivatives were then screened for biological significance and found to be the leading candidates against α-amylase and α-glucosidase enzymes. Al...