Icariin Ameliorates Palmitate-Induced Insulin Resistance Through Reducing Thioredoxin-Interacting Protein (TXNIP) and Suppressing ER Stress in C2C12 Myotubes

Both thioredoxin-interacting protein (TXNIP) and endoplasmic reticulum (ER) stress are implicated in skeletal muscle insulin resistance. Icariin has been found to mimic insulin action in normal skeletal muscle C2C12 cells and display anti-diabetic properties in diet-induced obese mice. However, the...

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主要な著者: Mingxin Li (著者), Yemin Zhang (著者), Yingkang Cao (著者), Deling Zhang (著者), Le Liu (著者), Yanghongyun Guo (著者), Changhua Wang (著者)
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出版事項: Frontiers Media S.A., 2018-10-01T00:00:00Z.
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