Icariin Ameliorates Palmitate-Induced Insulin Resistance Through Reducing Thioredoxin-Interacting Protein (TXNIP) and Suppressing ER Stress in C2C12 Myotubes

• 主要な著者: Mingxin Li (著者), Yemin Zhang (著者), Yingkang Cao (著者), Deling Zhang (著者), Le Liu (著者), Yanghongyun Guo (著者), Changhua Wang (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Both thioredoxin-interacting protein (TXNIP) and endoplasmic reticulum (ER) stress are implicated in skeletal muscle insulin resistance. Icariin has been found to mimic insulin action in normal skeletal muscle C2C12 cells and display anti-diabetic properties in diet-induced obese mice. However, the...