Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum

• मुख्य लेखकों: Dan-Qian Chen (लेखक), Gang Cao (लेखक), Hui Zhao (लेखक), Lin Chen (लेखक), Tian Yang (लेखक), Ming Wang (लेखक), Nosratola D. Vaziri (लेखक), Yan Guo (लेखक), Ying-Yong Zhao (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: SAGE Publishing, 2019-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: Acute kidney injury (AKI) is one of the major risk factors for progression to chronic kidney disease (CKD) and renal fibrosis. However, effective therapies remain poorly understood. Here, we examined the renoprotective effects of melatonin and poricoic acid A (PAA) isolated from the surf...