PARP inhibitors combined with radiotherapy: are we ready?

• Päätekijät: Chen Sun (Tekijä), Alan Chu (Tekijä), Rui Song (Tekijä), Shijia Liu (Tekijä), Ting Chai (Tekijä), Xin Wang (Tekijä), Zongwen Liu (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2023-10-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

PARP was an enzyme found in the nucleus of eukaryotic cells that played a crucial role in repairing damaged DNA. Recently, PARP inhibitors have demonstrated great potential in cancer treatment. Thus, the FDA has approved several small-molecule PARP inhibitors for cancer maintenance therapy. The comb...