Small Natural Cyclic Peptides from DBAASP Database

• Main Authors: Evgenia Alimbarashvili (Author), Natia Samsonidze (Author), Maia Grigolava (Author), Malak Pirtskhalava (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antimicrobial peptides (AMPs) are promising tools for combating microbial resistance. However, their therapeutic potential is hindered by two intrinsic drawbacks-low target affinity and poor in vivo stability. Macrocyclization, a process that improves the pharmacological properties and bioactivity o...