Adipose-specific knockout of ubiquitin-conjugating enzyme E2L6 (Ube2l6) reduces diet-induced obesity, insulin resistance, and hepatic steatosis

• Main Authors: Weiping Wei (Author), Yunqian Li (Author), Yongyong Li (Author), Daoyuan Li (Author)
• 格式: 圖書
• 出版: Elsevier, 2021-04-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Ubiquitin/ISG15-conjugating enzyme E2 L6 (UBE2L6/Ube2l6) catalyzes protein ISGylation and ubiquitylation, post-translational modifications which regulate protein stability. Ube2l6 plays a role in promoting in vitro adipogenesis; however, its mechanism(s) of action and in vivo effects remain unknown....