Inhibitory effect of donepezil on bradykinin-induced increase in the intracellular calcium concentration in cultured cortical astrocytes

• Główni autorzy: Kouki Makitani (Autor), Shota Nakagawa (Autor), Yasuhiko Izumi (Autor), Akinori Akaike (Autor), Toshiaki Kume (Autor)
• Format: Książka
• Wydane: Elsevier, 2017-05-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Donepezil is a potent and selective acetylcholinesterase inhibitor developed for the treatment of Alzheimer's disease. In the present study, we investigated the responses of astrocytes to bradykinin, an inflammatory mediator, and the effect of donepezil on these responses using cultured cortica...