Glycyrrhizin arginine salt protects against cisplation-induced acute liver injury by repressing BECN1-mediated ferroptosis

• Main Authors: Jun Guo (Author), Jiameng Yin (Author), Pu Liu (Author), Xin Zhang (Author), Jie Wei (Author), Mingjun Wang (Author), Yanxia Xiao (Author), Yongzhan Zhen (Author), Yajun Lin (Author), Jian Li (Author)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2023-09-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

The study aimed to investigate the protective effects and biological mechanisms of glycyrrhizin arginine salt (Gly-Arg) against cisplatin (Cis)-induced liver injury. Our data showed that Gly-Arg improved Cis-induced liver injury. Further study showed that BECN1 (beclin1) and LC3-II/LC3-I protein exp...