Immunohistochemical expression of programmed death-ligand 1 and CD8 in glioblastomas

• Main Authors: Dina Mohamed El Samman (Author), Manal Mohamed El Mahdy (Author), Hala Sobhy Cousha (Author), Zeinab Abd El Rahman Kamar (Author), Khaled Abdel Karim Mohamed (Author), Hoda Hassan Abou Gabal (Author)
• Format: Book
• Published: Korean Society of Pathologists & the Korean Society for Cytopathology, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Glioblastoma is the most aggressive primary malignant brain tumor in adults and is characterized by poor prognosis. Immune evasion occurs via programmed death-ligand 1 (PD-L1)/programmed death receptor 1 (PD-1) interaction. Some malignant tumors have responded to PD-L1/PD-1 blockade treat...