Searching for novel antagonists of adenosine A1 receptors among azolo[1,5-a]pyrimidine nitro derivatives

• Main Authors: Dmitry S. Yakovlev (Author), Pavel M. Vassiliev (Author), Yana V. Agatsarskaya (Author), Anastasia A. Brigadirova (Author), Kira T. Sultanova (Author), Maria O. Skripka (Author), Alexander A. Spasov (Author), Konstantin V. Savateev (Author), Vladimir L. Rusinov (Author), Dmitriy V. Maltsev (Author)
• 格式: 圖書
• 出版: Belgorod National Research University, 2022-06-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Introduction: Ligands of adenosine A1Rs are potential candidates for the development of drugs for the treatment of paroxysmal supraventricular tachycardia, angina pectoris, hypertriglyceridemia, type 2 diabetes mellitus, neuropathic pain, and heart failure. At the same time, there is a deficiency of...