Functional characterization, structural basis, and protein engineering of a rare flavonoid 2'-O-glycosyltransferase from Scutellaria baicalensis

• Main Authors: Zilong Wang (Author), Xueqing Du (Author), Guo Ye (Author), Haotian Wang (Author), Yizhan Liu (Author), Chenrui Liu (Author), Fudong Li (Author), Hans Ågren (Author), Yang Zhou (Author), Junhao Li (Author), Chao He (Author), De-An Guo (Author), Min Ye (Author)
• Format: Book
• Published: Elsevier, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glycosylation is an important post-modification reaction in plant secondary metabolism, and contributes to structural diversity of bioactive natural products. In plants, glycosylation is usually catalyzed by UDP-glycosyltransferases. Flavonoid 2'-O-glycosides are rare glycosides. However, no UG...