Fecal Host Transcriptomics for Non-invasive Human Mucosal Immune Profiling: Proof of Concept in Clostridium difficile Infection

• Автори: Robert Schlaberg (Автор), Amanda Barrett (Автор), Kornelia Edes (Автор), Michael Graves (Автор), Litty Paul (Автор), Jenna Rychert (Автор), Bert K. Lopansri (Автор), Daniel T. Leung (Автор)
• Формат: Книга
• Опубліковано: Case Western Reserve University, 2018-09-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Background: Host factors play an important role in pathogenesis and disease outcome in Clostridium difficile infection (CDI), and characterization of these responses could uncover potential host biomarkers to complement existing microbe-based diagnostics. Methods: We extracted RNA from fecal samples...