Fecal Host Transcriptomics for Non-invasive Human Mucosal Immune Profiling: Proof of Concept in Clostridium difficile Infection

• Main Authors: Robert Schlaberg (Author), Amanda Barrett (Author), Kornelia Edes (Author), Michael Graves (Author), Litty Paul (Author), Jenna Rychert (Author), Bert K. Lopansri (Author), Daniel T. Leung (Author)
• Format: Book
• Published: Case Western Reserve University, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Host factors play an important role in pathogenesis and disease outcome in Clostridium difficile infection (CDI), and characterization of these responses could uncover potential host biomarkers to complement existing microbe-based diagnostics. Methods: We extracted RNA from fecal samples...