Pan-cancer patterns of cuproptosis markers reveal biologically and clinically relevant cancer subtypes

• Główni autorzy: Fanqin Bu (Autor), Xiangji Li (Autor), Yu Zhao (Autor), Liyi Bai (Autor), Shutian Zhang (Autor), Li Min (Autor)
• Format: Książka
• Wydane: BMC, 2023-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Cuproptosis is a newly discovered type of cell death triggered by copper accumulation. Here we exhibited the genetic profiles of 10 cuproptosis-associated genes (CuAGs) across 21 cancer types. Only 8.0% (627/7839) of tumors possessed at least 1 mutation on CuAGs, while the copy number ampli...