Pan-cancer patterns of cuproptosis markers reveal biologically and clinically relevant cancer subtypes

• Main Authors: Fanqin Bu (Author), Xiangji Li (Author), Yu Zhao (Author), Liyi Bai (Author), Shutian Zhang (Author), Li Min (Author)
• Format: Book
• Published: BMC, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Cuproptosis is a newly discovered type of cell death triggered by copper accumulation. Here we exhibited the genetic profiles of 10 cuproptosis-associated genes (CuAGs) across 21 cancer types. Only 8.0% (627/7839) of tumors possessed at least 1 mutation on CuAGs, while the copy number ampli...