Kinase Inhibitor Library Screening Identifies the Cancer Therapeutic Sorafenib and Structurally Similar Compounds as Strong Inhibitors of the Fungal Pathogen <i>Histoplasma capsulatum</i>

• Main Authors: Charlotte Berkes (Author), Jimmy Franco (Author), Maxx Lawson (Author), Katelynn Brann (Author), Jessica Mermelstein (Author), Daniel Laverty (Author), Allison Connors (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<i>Histoplasma capsulatum</i> is a dimorphic fungal pathogen endemic to the midwestern and southern United States. It causes mycoses ranging from subclinical respiratory infections to severe systemic disease, and is of particular concern for immunocompromised patients in endemic areas. C...