The effects of dipeptidyl peptidase-4 on cardiac fibrosis in pressure overload-induced heart failure

• Main Authors: Masanori Hirose (Author), Hiroyuki Takano (Author), Hiroshi Hasegawa (Author), Hiroyuki Tadokoro (Author), Naoko Hashimoto (Author), Genzo Takemura (Author), Yoshio Kobayashi (Author)
• Format: Book
• Published: Elsevier, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dipeptidyl peptidase-4 (DPP-4) inhibitors are hypoglycemic agents. DPP-4 inhibitor has cardioprotective effects after transverse aortic constriction (TAC), but role of DPP-4 on cardiac fibrosis after TAC is not well known. Our aim was to determine the effects of DPP-4 on cardiac fibrosis in murine T...