Optimized Therapeutic ¹⁷⁷Lu-Labeled PSMA-Targeted Ligands with Improved Pharmacokinetic Characteristics for Prostate Cancer

• Main Authors: Yitian Wu (Author), Xiaojun Zhang (Author), Xiaojiang Duan (Author), Xing Yang (Author), Feng Wang (Author), Jinming Zhang (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Clinical trials have shown the significant efficacy of [¹⁷⁷Lu]Lu-PSMA-617 for treating prostate cancer. However, the pharmacokinetic characteristics and therapeutic performance of [¹⁷⁷Lu]Lu-PSMA-617 still need further improvement to meet clinical expecta...