The statistical approach in trial-based economic evaluations matters: get your statistics together!

• Main Authors: Elizabeth N. Mutubuki (Author), Mohamed El Alili (Author), Judith E. Bosmans (Author), Teddy Oosterhuis (Author), Frank J. Snoek (Author), Raymond W. J. G. Ostelo (Author), Maurits W. van Tulder (Author), Johanna M. van Dongen (Author)
• Format: Book
• Published: BMC, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Baseline imbalances, skewed costs, the correlation between costs and effects, and missing data are statistical challenges that are often not adequately accounted for in the analysis of cost-effectiveness data. This study aims to illustrate the impact of accounting for these stati...